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The No. 8 USC Trojans are heavy favorites against the visiting Colorado Buffaloes in this Pac-12 matchup on Friday at 9:30 p.m. Eastern on FS1. Here’s Pigskin Profit’s college football pick tonight:
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Colorado (+34.5) over USC (BetMGM)
If not now, never. The Trojans will put up 50 or so and quarterback Caleb Williams will continue climbing the Heisman Trophy rankings.
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But a defense allowing an average of 5.8 yards per play (ranked 95th) makes it difficult to envision USC running the table.
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