INDIE film-style quirki ness meets magical real ism to disarming and irritating effect in “End Days.” You can guess the flavor of Deborah Zoe Laufer’s play just by knowing its characters include a precocious, Goth teenage girl, a 16-year-old boy in an Elvis jumpsuit, Jesus and the physicist Stephen Hawking.

Rounding out this idiosyncratic cast are Arthur, the girl’s father, who’s lapsed into a post-9/11 depression and spends his days in his pajamas; and her mother, Sylvia, a former Jew turned atheist turned born-again Christian, who literally hangs out with Jesus while preparing for the upcoming Rapture.

“I’m off to battle Satan!” she cheerily announces before heading out to proselytize.

It takes the arrival of the perky, Elvis-loving Nelson (Dane DeHaan) to shake Rachel (Molly Ephraim) and her parents out of their funk. With his help, Rachel awakens to the joys of love and science, helped in the latter department by Hawking (Paco Tolson, doing double duty as Jesus), who offers acerbic robotic-voiced advice while tooling around in his motorized wheelchair.

Arthur (Peter Friedman) overcomes his stupor to help Nelson prepare for a belated bar mitzvah. After years of forgetting to eat, Arthur suddenly develops a ravenous appetite, whipping up Reuben sandwiches and waffles with abandon.

The newly evangelical Sylvia (Deirdre O’Connell) is a tougher nut to crack, but she, too, eventually sees the light when the day of the Rapture comes and goes.

The cloyingly precious nature of the proceedings is leavened by the witty dialogue and appealing performances all around. The playwright’s affection for her characters comes through clearly, resulting in a warmly moving evening containing a valuable message for troubled times.

END DAYS Ensemble Studio Theatre, 549 W. 52nd St.; 212-352-3101. Through April 19.