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CLEARSTEM is on sale for Amazon’s Big Spring Sale, and if you have a face — or a hormonal system that occasionally betrays you — you need to pay attention.

I’ve tried a lot of skincare, most of it overpriced, overhyped, and underwhelming. I also have perioral dermatitis and hormonal acne, the Bonnie and Clyde of broken skin barrier dysfunction. But CLEARSTEM? It’s one of the few brands that actually delivers.

The GENTLECLEAN cleanser is the citrusy, non-stripping face hug I never knew I needed in a face wash. And the MINDBODYSKIN supplement? It has its own shrine in my beauty arsenal.

If I could legally marry a supplement, I would’ve walked down the aisle with MINDBODYSKIN already. Yes, mostly for the financial benefits as it’s not the cheapest, but that’s what Amazon’s Big Spring Sale is for. It cleared (yes, cleared) my jawline breakouts, kept my hormones in check, and somehow made me feel more grounded — without messing with my mood (no 5-HTP, but they do have another option with it).

These products are well-intentioned, well-made, clean, and genuinely effective. And right now, they’re on sale. So, if you’ve been waiting for a sign to upgrade your skincare for some of the best on the market, this is it — preferably with two-day Prime shipping.

I don’t say this lightly: This supplement changed my life. MINDBODYSKIN is a daily hormonal acne supplement that actually works and doesn’t poison other parts of your body to do it. The real MVP ingredients? DIM (Diindolylmethane), which helps balance estrogen; vitex (aka chasteberry), a powerful hormone stabilizer; zinc, a known acne-fighter; and milk thistle to support liver detox, which is key when your skin is purging.

Also in the mix: turmeric, vitamin A, and selenium — all working together to calm inflammation, regulate oil production, and heal breakouts from the inside out. No fillers. No fluff. And crucially, no 5-HTP, which can interact with antidepressants if you take them. I saw results in just under two weeks, and my skin hasn’t been clearer in ten years.

This cleanser feels like a soft reset for your face every time you use it. It’s gentle enough to use daily, even on sensitive or acne-prone skin, but it still does the job. Vitamin C gives your skin a brightening boost, while green tea, goldenseal, and arnica calm any redness or irritation. There’s also mango extract, which makes it smell subtly like a tropical daydream without being overpowering.

The texture is lightweight and silky, with a soft lather that doesn’t strip your skin barrier — which, let’s be honest, most acne cleansers absolutely bulldoze. It’s perfect for a minimalist routine or as your AM cleanse before actives.

CLEARITY is your new ride-or-die if your pores are screaming or your skin texture feels like braille. The star ingredient is mandelic acid, a gentle AHA derived from bitter almonds that exfoliates without irritation, making it perfect for sensitive or acne-prone skin. It also includes turmeric, vitamin C, green tea, and EGCG — a potent antioxidant that helps soothe and reduce redness while unclogging congested pores.

Mandelic acid has a larger molecular structure than glycolic or lactic acid, so it works more slowly, meaning less chance of irritation. It’s also antibacterial, so it doubles as a breakout treatment and a glow enhancer. I recommend using it at night under CELLRENEW for maximum glow-up synergy.

HYDRAGLOW is rich but breathable and formulated with botanical stem cells, bakuchiol (a gentle, plant-based retinol alternative), squalane, and green tea. It deeply hydrates while also boosting collagen and improving elasticity over time. What I love is that it gives you that radiant, dewy finish without clogging pores or overwhelming oily skin. It’s non-comedogenic, calming, and somehow makes you look lit-from-within in the least greasy way possible. Use it day or night, under makeup or solo — it’s versatile and feels like skincare luxury with a purpose.

Prime Day is Amazon’s biggest sale of the year, offering deep discounts on bestsellers and everyday essentials. This year’s event runs from Tuesday, June 23 at 3 a.m. ET through Saturday, June 27at 3 a.m. ET.

This year, shoppers can take advantage of four days of Prime Day deals: Tuesday, June 23 at 3 a.m. ET through Saturday, June 27at 3 a.m. ET.

In addition to pushing up the sale to June, Amazon is including several new programs and promotions, including:

Prime Day and all its amazing discounts are exclusively available to Prime members. However interested shoppers can grab a 30-day free trial to try Prime, and its many benefits with no strings attached, and gain access to exclusive deals and the convenience of fast, free shipping.

From reporting on Amazon sales for years, we can tell you for certain that Prime Day is the ideal time to stock up on beauty and skincare staples, score big-ticket tech for less, bestselling vacuums, and comb through the massive catalog of Amazon best-sellers. Plus, since this year’s sale runs before the Fourth of July Americana-themed deals and summer hosting essentials.

We certainly think so! Prime Day is a great chance to score deals on thousands of best-sellers, top tech and appliances and every day essentials. Our team diligently sorts through all the offers to find you only the very best items to grab on sale.

Already wondering when Amazon’s next Prime Day is? We expect Amazon’s October Prime Big Deal Days sale event to return in fall 2026. Follow Post Wanted’s around-the-clock coverage, and you’ll be the first to know about headline-worthy sales. Click here to find all of the best deals.

For over 200 years, the New York Post has been America’s go-to source for bold news, engaging stories, in-depth reporting, and now, insightful shopping guidance. We’re not just thorough reporters – we sift through mountains of information, test and compare products, and consult experts on any topics we aren’t already schooled specialists in to deliver useful, realistic product recommendations based on our extensive and hands-on analysis. Here at The Post, we’re known for being brutally honest – we clearly label partnership content, and whether we receive anything from affiliate links, so you always know where we stand. We routinely update content to reflect current research and expert advice, provide context (and wit) and ensure our links work. Please note that deals can expire, and all prices are subject to change.