An already tumultuous season is teetering on disaster for the Titans, who lost starting quarterback Ryan Tannehill (ankle) for the regular season and will be without nearly a dozen other players for Thursday’s tilt against the Cowboys.

Some of that is by necessity; some of it seems by choice. Either way, oddsmakers are expecting a blowout win in Dallas’ favor in a game that clearly means more to the visiting side.

Here’s how we’re betting Thursday’s contest, which kicks off at 5:15 p.m. ET on Amazon Prime Video.

I desperately want to make the case for why the Titans are worth betting here as double-digit underdogs. I really do. But they’re making it harder to do by the day.

It was already a tough enough case to back Tennessee, which has lost five straight to fall below .500 for the first time since Week 3. This season reached a new low point with last week’s loss to the last-place Texans in arguably Malik Willis’ worst showing to date – throwing two interceptions and finishing with fewer than 100 passing yards for his third time in as many starts.

Then came the injury report on Wednesday, which promoted the biggest adjustment yet in the betting market for a game that’s been on the move all week. Derrick Henry (hip), the lynchpin of this Titans offense, is doubtful after limited practice. Jeffery Simmons (ankle), perhaps the best player on the roster and the lone bright spot of an otherwise horrid defense, has already been ruled out.

Then came the news that Willis was benched for journeyman third-stringer Josh Dobbs. That’s when the line moved even farther – to -14.

Those three are among ten regular starters who could be missing from Thursday’s action, leaving an already incompetent roster without many answers. Tennessee already ranked 24th in DVOA and 25th in point differential (-43), and last week’s loss to the worst team in the league shows just how much lower this team can fall without its key pieces.

Here’s the issue: the Cowboys aren’t exactly a sure bet at this number. Yes, Dallas is a top-five team by virtually metric and boasts one of the best rosters in football, but it’s also struggled to pull away from its competition in recent weeks.

Speaking of those lowly Texans, the ‘Boys needed all 60 minutes to escape their in-state foes in a 27-23 win in Week 14. They let the Jaguars hang around in an overtime collapse the following week, only to fall behind by 10 points in last week’s comeback win against the Gardner Minshew-led Eagles (a game they did end up winning).

All of that should give any bettor pause before laying the second-biggest number in the history of Thursday Night Football. If that sounds outlandish, consider the motivation: this game means virtually nothing to the Titans, whose playoff hopes rest almost entirely on next week’s game against the Jaguars that will decide the AFC South crown.

That’s a major reason why so many key players will be sidelined on Thursday – including four of Tennessee’s five starting offensive linemen from opening day, leaving Dobbs vulnerable against this potent Cowboys pass rush. It’s also a major reason why the Cowboys opened as such big favorites in the first place, even before Wednesday’s pivotal injury report and Thursday’s benching.

If you’re gun-shy on laying the points here but want to fade the Titans in other ways, consider betting the under on Tennessee’s team total (14.5), or even lay the touchdown on Dallas in the first half. Regardless of those side bets, I’m still willing to pay the price here on the Cowboys running away with a game that’s been practically gifted to them by the Titans’ coaching staff before it even starts.