JPMorgan Chase, led by CEO Jamie Dimon, has signed a lease for 436,905 square feet at L&L Holding’s 390 Madison Ave., the new office tower at 46th Street.

The deal brings the 850,000 square-foot building to full occupancy.

The bank will occupy 16 full floors and two street-level storefronts at 390 Madison.

The building has previously signed Shiseido Americas Corp. and law firm Hogan Lovells.

Previously known as 380 Madison, the new address reflects that the structure was “re-massed” on the bones of the original.

JPMorgan Chase also plans to replace its headquarters at 270 Park Ave. with a larger, taller building.