Jay Leno is staying upbeat amid his wife Mavis Leno’s dementia diagnosis.

The former late-night host, 73, filed for conservatorship on Friday over his spouse as she battles the disease.

He broke his silence on her condition when approached by the Daily Mail earlier this week while driving with two male pals.

“She’s fine. Everybody’s good, we’re doing well,” the comedian said, as he gave a thumbs-up from the driver’s seat of his vintage car.

Leno continued: “[I] set up a will, in case something happens.”

On Sunday night, the former “Tonight Show” host and his wife, 77, took in a show at the Comedy & Magic Club in Hermosa Beach, Calif.

Leno was performing a set that day at the venue.

The pair smiled and waved to onlookers as they made their way in. The couple married in 1980 and have no children.

TMZ reported on Jan. 26 that Leno filed legal documents to become conservator of Mavis’ estate.

While news of the filing only surfaced this month, the papers were drawn up in November.

According to docs, a hearing is set for April 9 in Los Angeles, with Mavis not being required to attend due to her “medical inability.”

Her “current condition renders her incapable of executing the estate plan,” the docs read.

Mavis currently “suffers from dementia, major neurocognitive disorder.”

“Unfortunately, Mavis has been progressively losing capacity and orientation to space and time for several years.”

“Jay is fully capable of continuing his support for Mavis’s physical and financial needs as he has throughout their marriage,” the docs also note.

Leno “believes … that Mavis consents to the conservatorship of the estate and to Jay’s appointment as her conservator and that she would not prefer anyone else to be appointed.”

The conservatorship comes more than a year after the “Jay Leno’s Garage” host got severely burned from a car fire in November 2022.

In January 2023, he also broke multiple bones from a motorcycle accident.

“That was the first accident. OK? Then just last week, I got knocked off my motorcycle. So I’ve got a broken collarbone. I’ve got two broken ribs. I’ve got two cracked kneecaps,” he told a Las Vegas Review-Journal reporter that month.

“So I turned down a side street and cut through a parking lot, and unbeknownst to me, some guy had a wire strung across the parking lot but with no flag hanging from it,” he explained at the time. “So, you know, I didn’t see it until it was too late. It just clotheslined me and, boom, knocked me off the bike.”

Leno added: “The bike kept going, and you know how that works out.”