The scuba-diving couple of “Open Water” are hardly the first to have their vacation go horribly awry: Hollywood has a history of mixing mai tais and mayhem.

DELIVERANCE (1972)

Four businessmen set off for a manly weekend of shooting the rapids. Things get seriously weird even before they hit the river.

Setting: Somewhere in the Appalachians

Spoiler(s): Toothless rednecks

Memorable line: “Squeal like a pig, boy!”

JAWS (1975)

It was supposed to be a day at the beach – until a mauled torso washed up on shore. The squeamish police chief, a prickly boat captain and a neurotic oceanographer set off to save the tourist season.

Setting: Massachusetts island called Amity

Spoiler: Great white shark with killer sense of timing Memorable line: “We’re going to need a bigger boat.”

NATIONAL LAMPOON’S VACATION (1983)

The Griswolds, headed by dad Chevy Chase, set off for the Disney-like WalleyWorld. Complications ensue.

Setting: Highways across the U.S.A.

Spoiler(s): Grumpy aunt, dead dog and that horrific amusement-park sign: “Closed.”

Memorable line: “We’re all gonna have so much f—ing fun, we’ll need plastic surgery to remove our goddamn smiles!”

WEEKEND AT BERNIE’S (1989)

Two businessmen are invited to their boss’ house for the weekend – but he gets whacked. The guys are forced to party on, arranging Bernie’s body so no one gets wise.

Setting: A beach house in the Hamptons

Spoiler: Bernie (body of)

Memorable line: “What kind of a host invites you to his house and dies on you?”

WHAT ABOUT BOB? (1991)

Dr. Leo Marvin is going on vacation – but that doesn’t stop Bob (Bill Murray), the shrink’s clingy new patient, who hops a bus and worms his way into Marvin’s paradise.

Setting: Lake Winnipesaukee, New Hampshire

Spoiler: Bob – or Dr. Marvin (Richard Dreyfuss), who spoils it for everyone else.

Memorable line: “You think he’s gone? He’s not gone. That’s the whole point! He’s never gone!”