Jane’s Addiction is no more.

The popular alt-rock band said it was breaking up Wednesday, more than one year after frontman Perry Farrell and guitarist Dave Navarro got into an explosive altercation during a concert in Boston last September.

“After that show, without notice to Perry, we unilaterally determined it would be best to not continue the tour and made inaccurate statements about Perry’s mental health which we regret,” the “Been Caught Stealing” rockers wrote on Instagram.

“Today we are here to announce that we have come together one last time to resolve our differences, so that the legacy of Jane’s Addiction will remain the work the four of us created together,” the group continued.

Navarro, bassist Eric Avery and drummer Stephen Perkins added that they “now look forward to the future as we embark on our separate musical and creative endeavors.”

“Jane’s Addiction will forever live in our hearts,” the band concluded. “We are proud of the music we created together.”

Farrell, meanwhile, issued a joint statement with Jane’s Addiction on his own Instagram page Wednesday.

He apologized for the onstage incident in Massachusetts, and further confirmed that the “Three Days” hitmakers were officially calling it quits after 40 years.

“I’d like to address what happened onstage last year,” Farrell, 66, began. “I’ve reflected on it and know I didn’t handle myself the way I should have. I apologize to our patrons and my bandmates for losing my temper and for disrupting the show.

“Jane’s Addiction has been at the center of my life for decades,” he continued. “The band, the songs, the patrons and the impact that we’ve had on music and culture mean more to me than any words I could ever possibly write down.”

The “Jane Says” singer apologized once more before thanking the group’s fans for their “love and support” all these years.

“My aim has always been to give our audience the best possible show, something real, honest and positive,” he explained. “In Boston, we fell short of that, and I’m truly sorry to everyone who was impacted.”

“From the bottom of my heart, I want to thank each and every one of you for your continued love and support,” Farrell ended his message.

Jane’s Addiction’s implosion began Sept. 13, 2024, during a reunion tour stop at Boston’s Leader Bank Pavilion, when Farrell and Navarro, 58, got into a physical altercation mid-performance.

Video from the concert showed Farrell shoving and striking Navarro as crew members rushed in to separate them, abruptly ending the concert.

The shocking incident prompted the band to cancel the remainder of its tour.

Farrell later issued a public apology, calling his behavior “inexcusable,” while Navarro, Avery and Perkins released a joint statement citing Farrell’s conduct as the reason the tour couldn’t continue.

Then, in July, Navarro, Avery and Perkins filed a lawsuit against Farrell seeking $10 million in damages.

Their suit alleged assault and battery, emotional distress, negligence and breach of contract, and the trio argued that Farrell’s actions both cost them significant touring revenue and derailed the group’s future music plans.

Farrell ultimately fired back with a countersuit hours later, accusing his now-former bandmates of harassment, bullying and contractual violations of their own.

He also disputed their characterization of the Boston incident and objected to statements made publicly about his mental health.

In 2022, Farrell gushed about Navarro and spoke about the future of Jane’s Addiction.

At the time, the band was hitting the road for its “Spirits on Fire” tour without Navarro, who was still recovering from COVID.

“Nothing great comes easy, and putting this tour together without Dave, you sometimes just have to accept what life deals you,” the “Stop!” singer told The Post three years ago.

“I wish I would have my dear guitar player around,” he continued. “[But] I live to bring entertainment and art to the world. And whatever I can do to entertain you, to blow your mind, that’s what I live for.”

Farrell added that he hoped Jane’s Addiction would continue playing together for at least another decade.

“But I’ve been performing music now for nearly 40 years, and I might have 10 more really good years to perform Jane’s Addiction material,” he told The Post. “Performing [that] material is like being an aerobics instructor, so I don’t know how great I’m going to be at 70.”