Fans of Dr. Lola Spratt rejoice: she’s back in action in “Medical Police” and saving the world — one virus at a time.

The 10-episode Netflix series is a spinoff from “Children’s Hospital,” Robb Corddry’s off-kilter, “Airplane!”-style medical spoof that aired on Adult Swim (2010-2016) and was one of the first series to originate on the web (in 2008 on TheWB.com).

The show boasted an ensemble cast including Corddry, Malin Akerman, Ken Marino, Henry Winkler, Lake Bell and Erinn Hayes as Lola Spratt — who takes the lead here along with Rob Huebel, reprising his “Children’s Hospital” role as Dr. Owen Maestro as the pair are deputized as secret government agents (don’t ask) chasing a bioterrorist around the globe.

“She’s the same character as she was in ‘Children’s Hospital’ — she’s the smartest dummy you’ll ever meet,” says Hayes, 43. “She and Maestro alternate between being total idiots and crazy-smart. You have to believe they live in a world where they are very smart doctors and then they’re … lovable a–holes.

“There are some inside jokes [from ‘Children’s Hospital’], but you don’t need to have watched any of that show to watch ‘Medical Police,'” she says. “In this series, Lola takes the lead and is at the forefront in following this viral outbreak along with Owen Maestro.”

While the series is focused mostly on Spratt and Maestro and their globetrotting sleuthing, Corddry, Winkler and the rest of the “Children’s Hospital” crew appear intermittently (they’re featured heavily in the premiere).

“They all come back, and it’s really fun as you go on in the show,” Hayes says, whose TV resume is a laundry list of series (including “The Dangerous Book for Boys” and a season-long stint on “Kevin Can Wait”). She says that “Children’s Hospital” was considered “dead in the water” when it ended in 2016.

“It was like, ‘We’re done. We told the story.’ It was a natural place to end the show,” she says. “It was a bit of a surprise for all of us in the cast [when it ended] … and then about a year later there started to be rumblings of, ‘Hey, maybe we can do this in a different format.’ I don’t like to believe anything until I’m in hair and makeup and on the set on Day One, but I started hearing about it … and the creators [Corddry, Jonathan Stern and David Wain] have more places to take this.”

The “globetrotting mystery action series,” as Hayes says (tongue-in-cheek), was filmed in and around LA (Chino Hills, San Dimas, downtown). The show also traveled on location to Zagreb, Croatia, which stands in for cities including Florence, Italy, Berlin and locales in Africa and Latvia. “We shot 10 days in Zagreb which, because of its history, has so many different eras of construction that you can find things that made it resemble those cities,” Hayes says.

The show’s future is undetermined at this point, but Hayes says the Season 1 finale leaves the door open for another season.

“It’s not like we have some crazy cliffhanger that demands an answer, but it does [leave open the possibility],” she says. “Fingers crossed that we’ll be able to see what else we can with this show and where it could go. I don’t know if viewers would want another season of just us solving worldwide crime, and I know the guys are already exploring options about what another season could look like.

“I want to do more of these.”