E! is spinning off “Keeping Up with the Kardashians” into a show starring sisters Khloe and Kourtney Kardashian.

The series, tentatively titled “Kourtney and Khloe in Miami,” will feature the sibs running the first East Coast franchise of their LA-based Dash boutique.

It’ll be produced by Ryan Seacrest, who produces “Keeping Up with the Kardashians,” and is slated to premiere in August.

Part of the show’s drama, according to E!, will revolve around Khloe’s decision to moonlight as a local radio host.