The new finding that acetaminophen — found in Tylenol — may dull empathy is alarming, but may not be as cut-and-dried as it seems. “This particular study should have no impact whatsoever on [which] painkiller to pick,” Dr. Elizabeth Loder, chief of the Division of Headache and Pain at Brigham and Women’s Hospital in Boston, tells The Post. Here’s a guide to the perks and pitfalls of the four most common over-the-counter pain pills.
Acetaminophen
AlamyWhile effective for lowering a fever, acetaminophen is a less effective painkiller because it doesn’t combat inflammation. It can also cause liver failure when combined with alcohol.
Aspirin
AlamyAvoid this if you take blood thinners or suffer from stomach bleeding. Ones that also pack caffeine, like Excedrin, are generally best at curing a migraine, but people unaccustomed to caffeine may risk withdrawal headaches.
Naproxen
AlamyNaproxen, found in Aleve, can temper a headache and manage inflammation from a sprain or arthritis, but recent research shows that it may heighten the risk of stroke or heart attack, even if you don’t have a history of heart problems.
Ibuprofen
AlamyThe same warnings that come with naproxen hold true for ibuprofen, the active ingredient in Advil. Beyond those risks, it’s an effective choice for dulling a hangover or menstrual cramps.



