Thanks to its ongoing tech boom, San Francisco continues to emerge as the West Coast’s small-town capital of cool. Here’s a look at the city’s newest must-tries from a late-spring weekend visit.

NYC’s Loews Hotels recently took over SF’s iconic Mandarin Oriental — which inhabited the top 11 floors in a 48-story skyscraper. Set in the heart of the Financial District, the new Loews Regency has been subtly updated and upgraded with 158 rooms, an 8,000-square-foot spa/fitness center, tasty, locally inspired brasserie and easily the best views in town.

Ultra-private and discreet, the hotel is a favorite of bold-named pop stars and their black-clad bodyguards (from $349).

Nothing better illustrates San Francisco’s new cultural confidence than the recently expanded SFMOMA. Opened in May at a cost of $305 million, the 10-floor addition was designed by Norway’s Snøhetta primarily to house the expansive collection of Gap founders Don and Doris Fisher. Boxy yet beautiful, the structure’s pale white, rippling facade evokes the fog and waters of San Francisco Bay.

Inside, look for the bluest of blue-chip works by crowd-pleasing minimalist and neo-expressionist talents such as Gerhard Richter, Georg Baselitz, Brice Marden, Agnes Martin, Anselm Kiefer and Ellsworth Kelly. Be sure to make time for a meal at In Situ, where chef Corey Lee deliver dishes inspired by top global toques such as Alice Waters, Thomas Keller and Wylie Dufresne.

The marvelously mad local design king Ken Fulk is the talent behind Leo’s Oyster Bar, a new Financial District seafoodery that he and fellow designer Jon de la Cruz created. Elegant and grown-up, the look is tropical luxe — think botanical wallpaper, rattan furniture and brass light fixtures, contrasted by a black-and-white tile floor and pink onyx bar.

The menu skews raw and fishy, from monumental oyster towers to instantly-addictive lobster rolls.

Vancouver-based cult skate-inflected fashion label STR/KE MVMNT opened its first US store on an unassuming stretch of SF’s still-grungy Polk Street. The gallery-like space stocks the brand’s full range of simple-yet-groovy apparel and accessories, including its line of gym-to-office-to-dinner trousers and hoodies.