CLEVELAND — Even the most dedicated Pinstriped Pollyanna knew the Yankees were due to hit a pot hole at some date — and that date has arrived.

Four out five losses isn’t enough to inspire overreaction, and the Yankees are still in first place after dropping a 5-2 decision to the Indians on Friday night in front of 31,531 at Progressive Field.

Nevertheless, Domingo German who not long ago was being mentioned as a possible AL All-Star, hasn’t pitched well in his last three outings. Luke Voit struck out four times Friday night and is mired in a 3-for-21 slide. Defensively there are plays that, although not scored errors, still have hurt.

Add in two runs in seven innings off Indians rookie pitcher Zach Plesac, who made this third big league start, and a quick two-hour and 23-minute game felt like a lot longer night to the Yankees.

“He mixed a couple of different breaking balls,’’ Aaron Boone said of former big league pitcher Dan Plesac’s nephew, who allowed two runs and six hits and watched his mates erase a 2-0 deficit with solo runs in the fourth and fifth and two in the sixth on Carlos Santana’s home run. “I felt we were going to get to him but he settled into a groove.”

Since they lost two of three to the horrific Blue Jays in Toronto and the first of three to the very pedestrian Indians, the best the Yankees can do is head home Sunday with a 3-3 record on this road trip.

Clint Frazier’s RBI double in the second inning and Aaron Hicks’ solo homer in the third staked German to a 2-0 lead, but after the second inning the Yankees didn’t send a batter to the plate with a runner in scoring position. And in the ninth, Voit, Gary Sanchez and Didi Gregorius, who went 2-for-4 in his first game of the season, were struck out by Brad Hand to end it.

“[Voit] is a little in between the last couple of days,’’ Boone said.

Through three innings, German looked like the hurler who went 8-1 with a 2.50 ERA in his first nine games (eight starts) when he gave up one hit that was erased when Sanchez threw out Jason Kipnis attempting to swipe second in the second inning.

A single by Oscar Mercado and a walk to Santana preceded Kipnis’ single to right that plated Mercado. Tyler Naquin, the No. 9 hitter, drove the first pitch through a 13-mph wind coming from right field into the seats for a 2-2 tie. Frazier took a deep route on Mercado’s leadoff fly toward right-center to start the sixth that fell for a single and Santana followed with a two-run homer to right.

“I tried to expand the zone with a change-up down and in for a double play,’’ German said of the pitch to Santana. “I left it high and he took advantage of it.’’

In his past three starts, German is 1-2 with an 8.79 ERA and suddenly the All-Star talk has been muted and the Yankees could intensify their search for a starter since nobody can predict when former staff ace Luis Severino will return from the injured list.

As usual, Boone was composed talking about German’s and Voit’s struggles, believing they will emerge from the funks. German is close to being the pitcher he was and Voit has gone through dips before, the manager explained.

Boone might be right because nobody can honestly say what that pair contributed in the first two months of the season can be described as flukes.

Yet, four out of five losses — two to a pitiful bunch and one to a mediocre crew — provides a reason to at least recognize a market reboot.