Maybe it’s a good thing Shohei Ohtani didn’t land with the Yankees.

The Bronx clearly doesn’t agree with the Angels’ two-way Japanese star — or at least the Yankee Stadium mound doesn’t.

For the second time in as many starts at the Stadium, Ohtani was roughed up by the Yankees, and this time his teammates couldn’t bail him out. Not against Nestor Cortes, the far superior pitcher, both on Thursday afternoon and so far this season.

Ohtani failed to record an out in the fourth inning and the Yankees hammered the Angels for the second straight time, 6-1, in the opener of a day-night doubleheader. Adding to his lost day on the mound, Ohtani was also picked off first base by Cortes in the fifth inning after his lone hit.

“They’re really good at reading pitches. They’re very good at it,” Angels manager Joe Maddon said.

When asked about Ohtani only registering three swings and misses on 75 pitches, Maddon said: “That’s unusual, very unusual. But I’m not accusing anybody of anything, except that they’re good at it. If you’re able to acquire things through natural means I’m all into it, I think it’s great.”

Yankees manager Aaron Boone, asked about his team’s ability to read pitches, said: “Hopefully we continue to be good at it.”

The game included an hour and 28-minute rain delay after eight innings that only delayed the inevitable victory by the Yankees (35-15).

Poor as this outing was, it wasn’t quite as bad as Ohtani’s first start in The Bronx, last June 30, when he was torched for seven earned runs on seven hits in two-thirds of an inning. The Angels rallied for an 11-8 victory that day with a seven-run ninth inning.

History didn’t repeat itself.

Cortes twirled seven shutout innings, lowering his ERA to a miniscule 1.50 — the second-lowest in all of baseball — while striking out seven and allowing five hits. It was the sixth start this year in which he yielded one earned run or fewer. That’s a stunning run for the former 36th-round pick who has come out of anonymity to be one of the premier pitchers in the game this year.

“I can’t sit here and tell you I don’t look at the numbers. I obviously look at the numbers. I look at everything everybody posts and everybody says,” Cortes said. “It’s been pretty special. … I try to compete. With that, I’ve had a lot of success.”

Ohtani, on the other hand, was frequently behind in the count and when he did get ahead, he couldn’t finish off hitters as his ERA rose to 3.99. He has a 27.00 ERA in two starts against the Yankees and has allowed 10 hits in 20 at-bats.

“Obviously they have a great lineup, and if I don’t make my pitches, they’re going to hit the ball hard,” Ohtani said through a translator after the Angels dropped their seventh straight game.

Matt Carpenter set the tone for the afternoon in the home first. Down 1-2 in the count, he fouled off five pitches in an 11-pitch at-bat. With each foul ball, the small crowd got more into it. On the final pitch, Carpenter launched a solo homer to right, a sign of Ohtani’s struggles to come.

Three batters later, Gleyber Torres went yard, and Aaron Judge took Ohtani deep in the third. The Angels righty allowed singles to the first two batters in the fourth, ending his shortest outing of the season. Marwin Gonzalez greeted reliever Jose Quijada with an RBI double and the Yankees added two runs an inning later to blow it open and get back to 20 games over .500.