With Johan Santana serving as the obvious headliner, the pitching matchups are now set for the season-opening series with the Reds that starts Monday afternoon at Great American Ball Park in Cincinnati. Here is the breakdown:

Monday — LHP Johan Santana (16-7, 2.53 last season) vs. RHP Aaron Harang (6-17, 4.78 last season), 1:10 p.m., SNY.

Tuesday — Off day.

Wednesday — RHP Mike Pelfrey (13-11, 3.72 last season) vs. RHP Edinson Volquez (17-6, 3.21 last season), 7:10 p.m., SNY.

Thursday — LHP Oliver Perez (10-7, 4.22 last season) vs. RHP Bronson Arroyo (15-11, 4.77 last season), 12:35 p.m., SNY.