DETROIT — Ron Gardenhire was ejected from his first game as manager of the Tigers after a replay review overturned what would have been the winning run in the 10th inning.

Nicholas Castellanos was initially called safe at home on a single by JaCoby Jones, and the Tigers spilled onto the field to celebrate. The play was reviewed, however, with the Detroit players still waiting on the field to hear the ruling.

After Castellanos was called out to end the inning, Gardenhire argued until he was tossed for the 74th time in his career.

With Gardenhire watching from afar, the Pirates got the better of the Tigers in the 13th inning when Gregory Polanco hit a three-run home run off Detroit reliever Alex Wilson. The Pirates held on to win 13-10.

Gardenhire, who previously had a lengthy tenure with the Minnesota Twins through 2014, was hired by Detroit to replace Brad Ausmus after last season.