CLEVELAND — After two relatively normal games between the Yankees and Guardians, the rubber match of the series went completely off the rails Wednesday.

The end result was a 4-3 comeback win for the Yankees, with Oswaldo Cabrera driving in the go-ahead run in the ninth inning to secure their fourth series victory in as many tries this season.

But the game got off to a bizarre start when manager Aaron Boone was ejected in the bottom of the first inning for arguing a controversial replay review that led to the Guardians scoring a pair of runs.

Second base umpire Larry Vanover, who made the call that was eventually overturned and also ejected Boone in the process, was later drilled in the head by a relay throw and had to go to the hospital.

The ricochet allowed the Yankees to score an extra run in the fifth inning during their comeback from a three-run deficit.

And who else but Franchy Cordero tied it all up with his fourth home run in his last five games, a 439-foot solo shot in the seventh inning.

Cabrera then delivered in the ninth, crushing a long single off Guardians closer Emmanuel Clase to drive in the winning run from second base.

“I think everybody was pretty pissed off [at the first inning],” said Clarke Schmidt, who was on the mound, making is third start of the season. “There was some aggression, for sure, from our side. … I think everybody had a little bit of a chip on their shoulder for the rest of the game.”

Clay Holmes added one last dash of drama in the bottom of the ninth, hitting a batter with a pitch and walking two more to load the bases with two outs. But he struck out Amed Rosario to end it.

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“It’s just a really good, gutsy win right there,” Boone said.

The game took a turn toward the wild side in the bottom of the first inning, with four weakly hit fly balls off Schmidt, three of them to shallow center field.

Aaron Hicks made a running and sliding attempt on all three.

He failed to come up with the first and then snagged the second.

On the third, with runners on second and third and one out, Hicks appeared to make the catch, after which he threw to second base to double off the runner, which would have ended the inning.

The Yankees ran off the field and the Guardians began to take it — after the 15-second timer teams normally get to challenge a play had run out — before the umpires huddled up to discuss the call on the field.

Initially, they had ruled that the runner on third base had tagged up and scored before the double play was completed, which would have meant a 1-0 Guardians lead and the end of the inning.

Then after convening, which negated the 15-second clock for the Guardians to challenge, the umps determined that the run had not scored in time, a decision that they brought to Cleveland manager Terry Francona, who promptly challenged it.

Replay reviews showed the ball did hit the ground, but Boone was ejected before that call was ultimately made, coming out of the dugout on four separate occasions during the elongated delay to argue his case.

“They got the play right, I will say that,” Boone said. “[But] I feel like the emotion of the building and the [play] being on the scoreboard, [the umpires decided], ‘Hey, no, let’s get together now.’ I thought that was wrong.”

“I feel like I should have caught that one,” Hicks said. “We had to go back out there because I didn’t complete the play.”

With their new life, the Guardians tacked on another run for the 2-0 lead before Schmidt was finally able to get out of the inning.

Schmidt later gave up another run in the third inning on a solo home run from Rosario that made it 3-0.

After Anthony Volpe led off the game with a double off the left-field wall, Guardians rookie right-hander Peyton Battenfield retired the next 13 Yankees before Cabrera singled with one out in the fifth inning.

That sparked a rally in which Kyle Higashioka drove in the Yankees’ first run with a long single, with another run coming in when the relay throw hit Vanover and allowed Isiah Kiner-Falefa to race home from third.

“That was a great come-from-behind win,” Boone said. “Just good to get out of here with a couple wins to finish off a good, strong trip against a really good Guardians team.”

“That was a great come-from-behind win,” Boone said. “Just good to get out of here with a couple wins to finish off a good, strong trip against a really good Guardians team.”