Austin Romine was confident he and Andy Pettitte wouldn’t have any problems working together in the catcher’s first game in the majors since 2011.

“It’s definitely easy to catch Andy,” Romine said before the game. “He knows what he’s doing with the ball.”

Last night, though, nothing was easy for the Yankees — and for a change, Pettitte didn’t really know what he was doing with the ball in a 9-1 loss to the Astros.

“I felt pretty good to start the game,” Pettitte said after getting knocked around for seven runs and 10 hits in 4 1/3 innings against a lineup filled with no-names and has-beens. “I felt like I threw a pretty good cutter to the No. 2 hitter. After that, it kind of abandoned me.”

And after striking out the No. 2 hitter, Brandon Barnes, Pettitte immediately unraveled.

He surrendered three runs in the first, but was even more upset by the two he coughed up in the fourth, when he hung an 0-2 cutter to Barnes and the right fielder belted a two-run double.

“It was up,” Pettitte said. “I’d been burying a lot of cutters in front of home plate to try to get a feel for it. … When you trust [a pitch] and it’s not there, it’s not a good feeling. I probably forced it a little too much.”

Romine, making his first appearance since being called up to replace injured Francisco Cervelli, couldn’t do anything to help Pettitte.

“We could have done a better job of getting on the same page,” Romine said. “I’ve got to get in his head.”

Pettitte took responsibility for not being able to find common ground with Romine.

“He hasn’t been back there and I felt like I didn’t get in rhythm I wanted to,” Pettitte said. “We didn’t do a good job of getting it done. He’s gonna be up here and he’s gonna be catching, so we’ll just continue to work on that and he’s gonna do a great job for us.”

The Yankees have to hope that’s the case, since Cervelli is out for at least six weeks after having surgery to repair a fractured right hand. As much as Cervelli impressed in the first month offensively, he made perhaps even more of an impact behind the plate.

Romine intends to continue that process when he gets back to the Stadium today.

“We’ve got to talk about what happened,” Romine said. “It’s gonna take a while to get on the same page. I’d like to do it a little bit quicker than what happened tonight.”