The Yankees leaned on their ability to come back to win the first three games of their series against the Mariners.

On Sunday, their offense stayed dormant for a full nine innings.

The Yankees had plenty of chances to change that but could never come up with the big hit, snapping their five-game winning streak with a 2-0 loss to the Mariners in The Bronx.

Missing one of their big bats in Anthony Rizzo, who tested positive for COVID-19 after Saturday’s game, the Yankees mustered six hits, went 0-for-11 with runners in scoring position and left 11 men on base.

“No excuses, we gotta get it done no matter what,” catcher Kyle Higashioka said. “We all know the burden that’s on us and we’re not going to shy away from it.”

The Yankees twice brought the tying run to the plate in the ninth inning, but DJ LeMahieu grounded out and Aaron Judge struck out looking to end the game.

Luke Voit, who was activated off the injured list before the game to replace Rizzo, had a rough first day back. He went 0-for-4 with two strikeouts, leaving the bases loaded in the third inning and stranding two more runners with a pop-out in the fifth.

The Yankees (61-50) lost for only the third time in their last 13 games, missing a chance to complete the sweep and wasting five more shutout innings from rookie right-hander Luis Gil.

“Anytime you’re in a close game, a low-scoring game like that and you do have some chances, that’s frustrating,” manager Aaron Boone said. “But we gotta get past it and get on with it now. But yeah, a chance to really do something special here to finish off this homestand and unfortunately we just couldn’t break through.”

To make matters worse, Gleyber Torres left the game with a left thumb injury — the severity not immediately known — sustained while diving into second base on a steal in the fourth inning.

The Mariners (59-54) broke a scoreless stalemate in the eighth inning off Lucas Luetge. After Abraham Toro reached on a fielding error by third baseman Rougned Odor and Luetge walked Mitch Haniger, Kyle Seager roped a ground-rule double to right field for the 1-0 lead.

Luetge came back to strike out the next two batters — including Jarred Kelenic, who was ejected for arguing the call — but Cal Raleigh followed with a single to left field. Two runs appeared to score but the Yankees challenged the second and got the call reversed — a strong throw from Joey Gallo nabbed Seager at the plate — to keep the deficit to 2-0.

Gil, who dazzled in his MLB debut Tuesday with six shutout innings against the Orioles, was called back up Sunday to make another start in place of Gerrit Cole (COVID-19). The 23-year-old wasn’t quite as sharp in his second start, but still came through with five shutout innings on two hits and two walks while striking out eight.

Before retiring seven straight Mariners to end his day, he escaped jams to keep the game scoreless. He worked around a single, error and walk with one out in the second inning to leave the bases loaded and then stranded runners on first and second in the third.

“When he wasn’t at his most dominant, you still see the swing-and-miss he has,” Boone said of Gil, who induced 17 swings-and-misses. “The stuff was still there. He made pitches when he had to and when he got into a little bit of a situation, he was able to find the strike zone. That was encouraging to see.”

Gil, who was returned to Triple-A Scranton/Wilkes-Barre after the game, became the first Yankees pitcher in 115 years to throw at least five scoreless innings in each of his first two career appearances.

But the Yankees offered him zero run support on Sunday, struggling to do anything against lefty Yusei Kikuchi or the Mariners bullpen.

“They held us down,” Boone said. “We had a couple chances there, they made a pitch and beat us today.”