The Knicks had Mitchell Robinson back on the practice floor as a full participant Wednesday for the first time since last year’s playoffs, as he moved ever closer to making his season debut soon after the All-Star break.

Just as they appeared to finally be back to full strength, however, workhorse guard Josh Hart was ruled out of Thursday’s home game against the Bulls with a right-knee injury.

Hart, who ranks third in the NBA in minutes per game (37.8) this season, had been listed as questionable or probable for several games before the break due to what the team had been terming right knee soreness. He had been playing through the issue, which now has been listed as patellofemoral syndrome, more commonly known as runner’s knee.

Hart underwent a debridement procedure on his right knee while with the Lakers in 2019.

Meanwhile, Robinson was cleared for and resumed 5-on-5 scrimmaging Wednesday for the first time since undergoing ankle surgery in May, and OG Anunoby also made it through the entire session, coach Tom Thibodeau said.

Robinson also was also ruled out for Thursday’s game, while Anunoby has been designated as questionable after missing the past five games leading up to the break with a sprained right foot.

“[They] did everything,” Thibodeau said. “[Robinson] he looks good. He’s gotta get his timing [back], but overall, he moved pretty well. … But it will take some time.”

Thibodeau acknowledged that the presence of the 7-foot Robinson eventually will make the Knicks’ rotation “a little different” with his ability to protect the rim and grab offensive rebounds.

“You have to anticipate that the game’s gonna be different, so we’ll see where he is once he’s out there,” Thibodeau said. “He’ll need a little bit of time.

“But the things that he can bring — the hustle, the ability to see things early, play pick and roll, rim-protect, offensive rebound — those are things he’ll bring right off the bat.”

Anunoby also benefited from the week-long respite, Thibodeau said, after the forward sat out the final five games before the break with a sprained right foot. Reserve guard Miles McBride also was back at practice after leaving last week’s game against the Hawks with a rib issue.

“It means a lot. Obviously after the break you want everyone to be ready to go,” All-Star guard Jalen Brunson said. “I’m excited to get down this stretch. I love this team a lot. I love everyone that’s a part of it and this organization.

“We all have one goal in mind, and I’m really thankful.”

The eventual returns of Robinson and Anunoby should help a Knicks team that ranks 18th in the NBA in defensive rating. The shot-blocking Robinson can serve as the backup to All-Star center Karl-Anthony Towns with the possibility of also being used in tandem — with Towns at power forward — against bigger front-court alignments.

“We’ve done a great job of sustaining what we need to do and being where we need to be right now at this point in the season,” Towns said. “The next-man-up mentality of the guys in the locker room has been great.

“To be able to get people — Mitch and everyone — back, it gives us a chance to hone in on our team as a whole.”

The Knicks, whose 36-18 record has them in the No. 3 position in the Eastern Conference, will be without Hart at least against the Bulls. They also will face the two teams ahead of them in the standings — the Cavaliers and the Celtics — on the road on Friday and Sunday.

“Whatever your circumstances are, you deal with them as best you can,” Thibodeau said. “We had guys out, so it was an opportunity for the new guys to get time together. So we tried to take advantage of it that way.

“Now that you have more depth, you take advantage of it the other way. You need everyone over the course of the season, so just get in there and get the job done.”