When it comes to setting weekly lineups, fantasy football managers run through an array of obstacles throughout the year. Navigating the bye weeks tends to be one of the biggest issues, followed closely by injuries to your players. But often times, we also can get tagged by the trickle-down effect when someone else’s player is the one out with an injury.

This week, we will see a few quarterback changes and, as such, changes in value for a number of rising fantasy stars.

No one is running to their waiver wire to add any receivers from the Lions, but now that Tim Boyle is expected to come off injured reserve to replace Jared Goff, those who have been using running back D’Andre Swift and tight end T.J. Hockenson may need to seek help elsewhere.

Goff’s oblique injury is going to put him on the shelf and for some reason, coach Dan Campbell feels Boyle, who has thrown a total of four passes in the NFL over the past two years, is the answer. Hockenson’s struggles have been well documented, so his value dips even further, but now facing the Browns pass-rush and 12th-ranked run defense, Swift’s job is going to be even more taxing. Volume is great if there’s running room, but the Browns have allowed the fifth-fewest rushing yards already and a stacked box is only going to make it tougher.

There is also trouble brewing for Jets rookie wide receiver Elijah Moore. With news that veteran Joe Flacco is making the start this week, there are numerous questions regarding the Jets’ young receiving corps.

Moore had seen an increase in targets over the past three weeks and has responded well with 16 catches for 195 yards and three touchdowns. Nevertheless, Flacco, who played five games for the Jets last year, has history with receiver Jamison Crowder and tight end Ryan Griffin.

As we often see with backups, they revert to what and who they know. Flacco may have only spent a short time with the Jets in 2021, but we can expect him to lean on familiarity in his first game as a starter this season.

In addition to these situations, you should also keep a watchful eye on Pittsburgh and Ben Roethlisberger’s status, Kyler Murray in Arizona and Lamar Jackson in Baltimore. All three are questionable for Sunday, but even if they play, will they be as effective at less than 100 percent? Always check your waiver wire before the games start and make sure, whether it’s your injury or not, you’re putting your best foot forward.

Howard Bender is the VP of operations and head of content at FantasyAlarm.com. Follow him on Twitter @rotobuzzguy and catch him on the award-winning “Fantasy Alarm Radio Show” on the SiriusXM fantasy sports channel weekdays from 6-8 p.m. Go to FantasyAlarm.com for all your fantasy football advice.