Nobody cares.

Nobody cares that the Giants are down a starting quarterback and have to start a backup, Colt McCoy, Sunday in Seattle.

Oh, the Giants care, certainly, and are strategizing day and night to come up with a plan of attack in which McCoy can survive and perhaps thrive. The Seahawks care, no doubt, and probably are licking their chops and affixing McCoy’s No. 12 jersey to targets after dropping Carson Wentz six times Monday night.

Around the league, who the heck cares? Daniel Jones is an ascending young player and his last 10 quarters contained promising signs that he is solving his turnover issues and developing into a more-than-capable, winning quarterback. That he is sure to miss this next game, dealing with a strained right hamstring, is angst-inducing for Giants loyalists but hardly resonates deeply in all corners of the NFL. Quarterbacks get hurt so often, it is almost a census-taking exercise every week. Who is in? Who is out? Next man up, as they say.

With Jones, the task for the Giants at what is now called Lumen Field would have been challenging. The Seahawks are 8-3 and lead the NFC West. They give up more yards and more points than Seattle defenses are accustomed to allowing but continue to ride the brilliance of Russell Wilson and the emergence of receiver DK Metcalf. Without Jones, the challenge is greater. There is no denying this. Impossible? No. Not even with McCoy, a 34-year-old who has made 28 NFL starts, but only three in the last five years.

Before the season, Pro Football Focus ranked all 32 backup quarterbacks. Jameis Winston (Saints) was No. 1. Marcus Mariota (Raiders) was No. 2. Andy Dalton (Cowboys) was No. 3. Joe Flacco (Jets) was No. 7. McCoy was No. 27.

Unfair? Not really. Still, the guy has a skill set, can move out of the pocket, knows how to run an offense and, the Giants hope, avoid ghastly mistakes. Here is where Jason Garrett, the offensive coordinator, must earn his money. The entire playbook will not be scrapped, but several pages designed especially for Jones will have to temporarily be removed.

Last week, McCoy was summoned, for the first time all season, in the third quarter in Cincinnati and he admitted he felt a bit rusty. His overthrow of a hot-read swing pass to Dion Lewis was proof. His toss to Golden Tate for a first down and sideline pass to Sterling Shepard for 13 yards on second-and-12 showed there is nothing wrong with McCoy’s arm. It is not a howitzer, but it is accurate enough.

“One of the hardest parts about him going in the game the other day and as a backup in general is you don’t get many reps with the first team running our system,’’ quarterbacks coach Jerry Schuplinski said Tuesday. “So credit to him for getting in there and being able to run everything. I mean, that’s his job but he did it well.’’

McCoy will hunker down this week and get all the first-team reps in practice, operating the starting offense instead of his usual role with the scout team. The work will do McCoy wonders.

Will this go smoothly? Most likely, no. Do the players around McCoy have to pick up the pace and rise above the X’s and O’s? The strong assumption is yes. Will all of this be enough to upset the Seahawks? The odds are against it, but that does not mean McCoy’s presence on the field makes this mission impossible.

The last time a Giants starting quarterback was injured and a career backup was summoned was 17 years ago. Kerry Collins had a sprained ankle and Jesse Palmer made his NFL starting debut, Dec. 14, 2003, at New Orleans. The Giants lost, 45-7. Palmer, excitable and personable, said, “I had a blast.’’ The next year, he was featured in “The Bachelor’’ and currently is must-see viewing among certain members of my household as the host of the “Holiday Baking Championship’’ on The Food Network.

There was never the need for a backup quarterback on the field during Eli Manning’s 16-year term. Jones’ high ankle sprain last year as a rookie forced him to miss two games — the last two starts of Manning’s career — and this hamstring injury has Jones on the shelf again. It happens almost everywhere. It is up to the Giants to make the most of a bad situation.