The Jets are missing essentially their starting quarterback, their best running back, several receivers and are playing with a stitched-together offensive line that is absent two first-round picks.

Every football team can point to a laundry list of injuries in December, but few teams have plummeted as deeply as the Jets have offensively the past few weeks. So much has gone so wrong during a three-game losing streak that has severely jeopardized their playoff hopes.

The Jets have scored four touchdowns in three games. The funk has featured two games started by Mike White and one by Zach Wilson, but the constant has been a disappearance of whomever is running the ball.

“Establishing the run game has been probably the most glaring [issue],” left tackle Duane Brown said at practice in Florham Park on Tuesday. “We pride ourselves on that. We’ve had some really great performances, but that’s kind of where it starts for us — having a good run game sets up so much for the pass game.”

That was the recipe when Wilson was handing off to Breece Hall, until the rookie standout was lost for the season in Week 7. The Jets added James Robinson, eventually unveiled Zonovan “Bam” Knight and kept rolling, averaging 4.5 yards per rushing attempt in their first 12 games.

In their past two, including a 50-rushing-yard dud in Sunday’s loss to the Lions, Jets running backs have averaged 2.9 yards per rush.

“It’s a little bit of everything,” said head coach Robert Saleh, who declined to dig into any schematic issues. “We’ve got to protect better, we’ve got to run better, [running] backs got to see it better.”

Unspoken are the losses of pieces such as Alijah Vera-Tucker and Mekhi Becton and the instability of an offensive line that has gone through constant change and constant injuries.

Brown could have undergone shoulder surgery before the season started, but the 37-year-old opted to play through the injury. Right tackle George Fant has been playing through a left knee injury.

Brown acknowledged he is “playing through some stuff,” but, “I’m out there. … If I’m out there, I’m good to go.”

He believes the running game will return beginning Thursday, when the Jets play the Jaguars at MetLife Stadium, and will not vanish again.

“[Running has] been a big point of emphasis for this week, and it’s a big point of emphasis for the rest of the year,” said Brown, who is in his 15th NFL season. “When you become one-dimensional, teams are going to pin their ears back and rush the passer. You don’t want to be in that type of game.”

The Jets were in that type of game Sunday, when there was no room for Knight or Michael Carter to run, which put a bigger burden on Wilson to throw — and a bigger burden on the offensive line to allow Wilson time to throw.

Wilson, who went 18-for-35 for 317 yards, two touchdowns and an interception in an uneven performance, was pressured on 37.5 percent of his passes, the most of a Jets quarterback this season. Wilson had been hit nine times in his first seven games this season. On Sunday, he was hit seven times.

The second-year quarterback, who will play Thursday because White (ribs) has not been medically cleared, holds on to the ball longer than White, but the Jets’ offensive line still protected him better earlier in the season.

When Wilson did have enough time, he did not have Corey Davis (concussion) or, for three quarters, Denzel Mims, who left in the first quarter with a concussion. The Jets’ second-leading receiver was seldom-used Jeff Smith, who later exited with a knee injury. Davis is expected to return Thursday, while the statuses of Mims and Smith, who did not practice Tuesday, are less certain.

The Jets may ask their running game, which has carried them for much of the season, to do so again, which would entail asking their offensive line to create the holes that existed earlier in the season.

According to Brown, the offensive line will respond.

“You can’t go out there thinking, ‘Oh, we’re banged up, we might not be at our best,’ ” Brown said. “If you’re out there, you gotta do your job.”