The Rangers sometimes operate like a chemistry lab.

Incorporate some cross-country travel, you get a flat start. Throw in a pinch of adversity and you sometimes get resiliency, as has been the case recently. But with the right components, the Rangers can explode for multiple goals no matter the situation or circumstance.

That was the case Saturday night at Madison Square Garden, when the Rangers erased another two-goal deficit and charged back with a whopping six unanswered tallies for a 7-3 victory over the Coyotes to kick off the second half of the season.

The Rangers’ seven goals, three of them by Chris Kreider, are the most they’ve scored in a game all season.

“Wild 48 hours for us,” said Jacob Trouba, who scored two goals and dished out an assist in his 150th game as a Ranger. “Took a little bit to get our legs and get our momentum going. But it’s good composure in between periods and I liked our game, stuck with it.

“We know we have a team that is capable of, I guess turning it on. You don’t want to rely on turning it on and off, but like I said, unique 48 hours for us and it’s good to be able to do that.”

Coming off a deflating loss to the Hurricanes on Friday night, the Rangers didn’t get back to New York until 4:15 a.m. due to weather delays in North Carolina. After the quick turnaround, mixed with some last-minute lineup changes after Kaapo Kakko was scratched following warm-ups with an upper-body injury, the Rangers resembled more of a fizzled-out firework through the first period, in which they fell behind 2-1 after getting outshot by an egregious 16-4 in the opening 20 minutes.

The odds continued to stack against the Rangers when Filip Chytil didn’t return to the bench following the first intermission after suffering what the team said was a lower-body injury. Clayton Keller then pulled the Coyotes ahead by two with a goal just over seven minutes into the second period, and the Rangers looked to be dead in the water against the second-to-worst team in the NHL.

But when Kreider scored shorthanded at 11:30 of the second, it not only cut the Rangers’ deficit to 3-2, but also served as a much-needed catalyst for his team’s winning formula.

“That was the biggest thing,” head coach Gerard Gallant said. “Definitely the shorthanded goal was huge for us. It was a big, big goal. It goes us back to 3-2 and it was definitely a momentum changer for sure.”

With another goal at the end of the second and a power-play tally in the third, Kreider led the Rangers with the second four-point night of his career. His 29 goals are a career best and tied him with Capitals scoring machine Alex Ovechkin for the NHL lead.

It was the fifth hat trick of Kreider’s 10-year NHL tenure, while his 14th power-play goal surpassed Oilers star Leon Draisaitl for the most in the league.

“Things have obviously been going great for him this year,” Trouba said of Kreider. “But he hasn’t really acted like things have been going great. He’s the same Chris, he knows what he’s good at, what makes him good.”

Julien Gauthier evened the score shortly after Kreider’s tally, finishing a play around the Coyotes’ net.

One could argue that Arizona’s top-line center Johan Larson then made the biggest mistake of the game: going after Adam Fox. Larson cross-checked Fox while he was down, before delivering a cheap shot to the back of his head, drawing the ire of every Ranger on the ice and every fan in blue in the building.

With Larson in the box, Artemi Panarin sniped a power-play goal to give the Rangers their first lead of the night, at 16:33 of the second. Kreider then buried a rebound after an odd-man rush to give the Rangers four goals in the span of 7:12 in the second period.

Trouba made it a 6-3 game just 1:33 into the third and Kreider closed out the scoring with a power-play goal for the hat trick.

“It’s not an easy thing to do to have a turnaround and get stuck where we were last night and get home late,” Trouba said. “But at the end of the day, this is your job. You work for three hours. Find a way to pull it together and show up.”