Jewelry designer Aurora Lopez Mejia is listing her Soho apartment for $4.95 million.

Her clients have included Debra Messing, who waited for the perfect — and hard-to-find — fire opal engraved with the word “imagine.”

Her one-bedroom, 1½-bathroom home at 145 Sixth Ave. — a 1900s-era “column-and-beam loft building” overlooking Hudson Square Park, is equally inspiring. The fourth-floor unit is a live/work loft space with ceilings over 11 feet high, custom dark wood beams, white oak floors, large entertaining areas and “uninterrupted” wall space to display art.

The home features steel sliding glass doors that open to a space that can fit an office, library or a guest bedroom with an ensuite bath.

The master bedroom features custom wood cabinetry and a spa-like marble bathroom.

There’s also an open chef’s kitchen.

The listing broker is Halstead’s Meylin Maldonado.