Robert Duffy, president of Marc Jacobs, has sold his posh 35 W. 12th St. townhouse for $5.5 million — far less than its original $8 million asking price.

The charming home, built around 1840, comes with four bedrooms and 2 ¹/₂ baths. Once featured in Architectural Digest, it also has decorative fireplaces, 11-foot ceilings, a new mahogany staircase and a garden.

The buyer is Rosalind Resnick, an ex-journalist turned real-estate investor who made her first fortune selling an e-mail marketing firm she had co-founded for $111 million in cash. She’s already listed the house with Compass as a $25,000-a-month rental.

Duffy’s been on a real-estate spree in recent years. He paid $10.25 million in 2013 for 62 W. 12th St. — an 1839 Federal-style townhouse — and also bought the Astor Tea House in Rhinebeck, which is part of the estate where Chelsea Clinton was married. Resnick said: “My dream was to own a townhouse in the West Village and be surrounded by books. Now I own eight of them.”