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Not all supplements are created equal. And, that’s hardly news.

The market is flooded with brands making bold health claims, and collagen is no exception. As a wellness writer, I’ve tried my fair share, and I’m often skeptical that I’ll see any real long-term difference in my hair, skin or nails. But if there’s one formula that’s catching my attention, it’s Elysium’s Cofactor.

This isn’t your ordinary collagen supplement. Cofactor blends clinically backed Premium Collagen Peptides, Hyaluronic Acid, Vitamin C and 250 milligrams of NR to support NAD+ levels — the coenzyme that biohacking enthusiasts have linked to cellular health and longevity. And right now, during Amazon’s Spring Sale, Cofactor is marked-down 35% off.

According to Elysium, Cofactor works by supporting your body’s natural ability to repair and maintain collagen — so it’s not just for hair, nails, skin elasticity and hydration, but also for overall vitality. Translation: internal and external benefits.

Reviewers are seeing the results, with one calling it the best collagen supplement they’ve tried. And that was just after the first month of use.

ELYSIUM Cofactor – 4-in-1 Collagen Peptides Powder w/NAD+

AmazonAmazon

“My skin feels noticeably more hydrated and has a healthy glow that wasn’t there before,” the reviewer shared, adding that they love that it combines collagen peptides with NAD+.

The unflavored powder blends easily into any cold liquid, and each pouch contains 28 daily servings for a full month of support. According to Elysium, consistent use can lead to enhanced skin hydration within weeks and smoother skin with fewer visible wrinkles over time. Some users report benefits even sooner.

“It feels like I’m supporting my skin and overall wellness at the cellular level,” they added. “After just a few weeks, I’ve also noticed my joints feel less stiff, especially in the mornings.”

more best-selling NaD+ supplements

NAD+, backed by results: Elysium’s top-selling Basis supplement is clinically proven to boost NAD+ levels by 40% in a double-blind, placebo-controlled trial.

$60.00 $48.00
Amazon
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If you’re ready to crank up your NAD+ levels, the TRU NIAGEN PRO NAD+ is a great place to start. This formula has been shown to increase NAD+ levels within three weeks and is backed by decades of research.

$49.00
Amazon
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The Liposomal NMN Pro Complete rapidly increases NAD+ levels and enhances cellular energy while optimizing mitochondrial performance. Triple-lab tested, thousands of consumers trust and use it.

$51.45
Amazon
Buy Now

Your Amazon Prime Day FAQs, answered

What is Amazon Prime Day and when is it?

Prime Day is Amazon’s biggest sale of the year, offering deep discounts on bestsellers and everyday essentials. This year’s event runs from Tuesday, June 23 at 3 a.m. ET through Saturday, June 27at 3 a.m. ET.

How long is Prime Day?

This year, shoppers can take advantage of four days of Prime Day deals: Tuesday, June 23 at 3 a.m. ET through Saturday, June 27at 3 a.m. ET.

What’s new about Prime Day in 2026?

In addition to pushing up the sale to June, Amazon is including several new programs and promotions, including:

  • Today’s Big Deals program: New daily discounts up to 50% off or more
  • New deals dropping as often as every five minutes during the sale
  • Prime members gain access to exclusive travel deals
  • Prime members who spend $15 or more on a qualifying online grocery order have a chance to win free groceries for a year
  • Prime members who set up a deal alert with Alexa have a chance to win a $1,000 Amazon gift card
  • Through June 26, Prime members can get a large pepperoni or cheese pizza from Little Caesars for $5
  • Through June 26, Prime members who purchase a new car through Amazon Autos get a $1,500 Amazon gift card

Do you have to be an Amazon Prime member to shop?

Prime Day and all its amazing discounts are exclusively available to Prime members. However interested shoppers can grab a 30-day free trial to try Prime, and its many benefits with no strings attached, and gain access to exclusive deals and the convenience of fast, free shipping.

What are the best deals?

From reporting on Amazon sales for years, we can tell you for certain that Prime Day is the ideal time to stock up on beauty and skincare staples, score big-ticket tech for less, bestselling vacuums, and comb through the massive catalog of Amazon best-sellers. Plus, since this year’s sale runs before the Fourth of July Americana-themed deals and summer hosting essentials.

Is it worth it?

We certainly think so! Prime Day is a great chance to score deals on thousands of best-sellers, top tech and appliances and every day essentials. Our team diligently sorts through all the offers to find you only the very best items to grab on sale.

When is the next Prime Day?

Already wondering when Amazon’s next Prime Day is? We expect Amazon’s October Prime Big Deal Days sale event to return in fall 2026. Follow Post Wanted’s around-the-clock coverage, and you’ll be the first to know about headline-worthy sales. Click here to find all of the best deals.

Why Trust Post Wanted by the New York Post

This article was written by Miska Salemann, New York Post Commerce Writer/Reporter. As a health-forward member of Gen Z, Miska seeks out experts to weigh in on the benefits, safety and designs of both trending and tried-and-true fitness equipment, workout clothing, dietary supplements and more. Taking matters into her own hands, Miska intrepidly tests wellness products, ranging from Bryan Johnson’s Blueprint Longevity Mix to the viral Oura Ring to Jennifer Aniston’s favorite workout platform – often with her adorable toddler by her side. Before joining The Post, Miska covered lifestyle and consumer topics for the U.S. Sun and The Cannon Beach Gazette.

Looking for a headline-worthy haul? Keep shopping Post Wanted.

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