Myles Powell was missing again.

Returning to the Prudential Center for his first home game since Nov. 23 — and first time since suffering a concussion, which sidelined him two games — the preseason All-American’s adrenaline was unmatched. Milliseconds separated his first touch from his first shot. His second, third and fourth shots followed similar journeys. Some attempts were forced. Each attempt came up empty.

The clock shed 11 ¹/₂ minutes before Powell produced a point. Another 12 ¹/₂ minutes passed before he would score again.

Still, Seton Hall put forth one of its best performances of the season.

The one-man show is no more.

Just over two weeks removed from upsetting No. 7 Maryland without its star senior, Seton Hall built a 20-point first-half lead over Georgetown with a brilliant defensive effort, and the balanced supporting cast led the Pirates to their season-best fourth straight victory, 78-62, on Friday night.

Though Powell was held to 15 points on 6-of-17 shooting from the field, Myles Cale (16 points) hit five first-half 3-pointers and Romaro Gill (17 points) produced his highest scoring output in two seasons with the team, while Quincy McKnight directed another impressive outing with 14 points, a season-high 10 assists and no turnovers.

The physical and disciplined defense of Seton Hall (10-4, 2-0 Big East) held the 80-point-per-game attack of Georgetown (10-5, 0-2) to less than 36 percent shooting from the field.

“We’re playing like the team everyone projected us to be,” Powell said. “It’s starting to show now. Everybody’s starting to learn their roles and realize what we need to do to win. We’re still not even our best. We’re at a great point right now. I feel like me getting hurt and us getting that big win against Maryland boosted these guys’ confidence. I feel like that was the best thing that could’ve happened to this team. And that’s coming from me.

“Everybody has bought in and is doing what they need to do. Just seeing these guys do what I knew they could do the whole time and start to believe in themselves, they’re doing everything that I can ask for right now.”

Cale — who entered averaging 7.3 points — followed up his season-best 16-point outing at DePaul with more evidence the Big East’s preseason favorite still can contend despite the absence of Sandro Mamukelashvili or rare off-nights from Powell.

Gill — who entered averaging 5.2 points — made 6-of-9 shots, with eight rebounds and four blocks, while holding Georgetown’s leading scorer, Omer Yurtseven, to a season-low nine points on 3-of-14 shooting.

“He doesn’t know what kind of impact he has,” Powell said of his roommate. “All we kept hearing about was their 7-footer, but we have one of the best 7-footers in the country.”

Inevitably, Powell’s presence was felt.

When Georgetown threw extra defenders his way, he compiled a season-high six assists. When the Hoyas sliced the lead to 11 with eight minutes remaining, Powell scored eight points, with an assist, in a game-clinching 10-0 run.

“That’s just Myles being Myles,” coach Kevin Willard said. “He’s just not back to where he’s going to be in a couple weeks, but you just knew it was only a matter of time.”