Chicago’s lovable losers stuck it to Hondo last night — just as they did Monday night — getting dinged in Detroit to trim the earnings to 280 gilliams.

Tonight, he’s woofing about Wolf — 10 units on the Dodgers to hose the Chisox.

$

Paul Giamatti reportedly could replace Sean Penn as “Larry” in the upcoming Three Stooges movie. That’s a shame, because Penn proved himself to be such a natural stooge during his visits with Hugo Chavez and the Castro Brothers . . . Penn said he bagged the movie in order to spend more time with his family, which is a tough break for his family . . . A-Rod, still looking tired, should do what Clemens did when he was feeling fatigued: Get a B-12 shot.

hondo@nypost.com