Our annual 50 NFL Most Fascinating list features a bit of a shake-up at the top. The dizzying quarterback, wide receiver and television carousel makes this our most fascinating Most Fascinating compilation to date.

Our new No. 1 represents a huge gamble for a proud franchise that has designs on a sixth Super Bowl championship and first since the 1994 season.

And No NFL 50 Most Fascinating list should omit the league’s most prominent brother duo who entertain and inform us on “Monday Night Football” on ESPN2 and ESPN+

49ers QB (2021 rank: 46)