Brandon Holt’s improbable U.S. Open run has come to an end in heartbreaking fashion.

After steamrolling through the first two sets in roughly an hour, the 24-year-old son of Hall of Famer and two-time U.S. Open champion Tracy Austin fell victim to Pedro Cachin’s thrilling five-set comeback and lost 6-1, 6-2, 1-6, 6-7 (1), 6-7(6) in front of jam-packed stands on Court 12 of the USTA Billie Jean King National Center grounds on Wednesday.

Cachin, who’s had back-to-back victories in a fifth-set tiebreak this tournament, will now face the 23-year-old Corentin Moutet in the third round on Friday.

In the deciding 10-point tiebreak, Cachin commanded a 6-3 lead before Holt unloaded whatever was left in the tank to even the score at six-all. However, Holt fumbled into three groundstroke errors as Cachin fired off a series of hard-hit shots. The three-hour, 44-minute marathon ultimately ended on Holt’s third double fault of the match.

Cachin collapsed, laid flat on his belly with his arms crossed in front of his face and let his emotions pour out onto the court.

Despite letting the opening two sets get away from him, Cachin stormed back into the match with conviction. In addition to winning 39 of 60 points at the net, the No. 66-ranked Argentine finished with 15 aces and 58 groundstroke winners. It quickly became too much for Holt, who looked gassed in the final two sets and was overwhelmed into 51 unforced errors.

As crushing as the loss presumably was, Holt will reap the benefits of his unforeseen run to the second round as a qualifier. The four-time All-American out of USC should see a bump in his ATP rankings, where he is listed at No. 303.

After a hand injury jeopardized his career several months ago, Holt worked his way back and became a headlining story of this tournament. At first, the attention was purely because of who his mother is. Austin became the youngest U.S. Open female singles champion when she won at age 16 and the youngest inductee into the International Tennis Hall of Fame when she earned the honor at age 29. Thirty singles titles will definitely draw attention to your offspring.

But Holt is now well on his way to establishing a notable career of his own.

After winning the first set on Wednesday, Madison Keys topped Italy’s Camila Giorgi in a third-set tiebreak to secure a 6-4, 5-7, 7-6 (10-7) win to advance to the third round against compatriot Coco Gauff.

“Honestly today I feel like I was probably a little bit too passive at times,” Keys said. “I think I let Camila dictate a bit too much. Trying to find that balance against her is really difficult; you don’t want to go toe-to-toe and overhit. Similar in the next match where I have to try to get ahead in the point against someone like Coco because you don’t want her to get the first strike.”

The 20th-seeded American, who fell to No. 87 in the rankings earlier this year, put up eight aces in comparison to Giorgi’s zero.