This time, it’s Seth Green. (If you haven’t seen him in “Can’t Hardly Wait,” you really need to.)

Microsoft and BioWare announced that he’ll be the voice of the Joker in “Mass Effect,” an Xbox 360 exclusive game. No stranger to le voice acting, Green can also be heard on “Family Guy” as Chris and on “Robot Chicken.”

Other announced voices appearing in the game include: Marina Sirtis (“Star Trek: The Next Generation”) as The Matriarch, Keith David (“Pitch Black”) as Captain David Anderson and Lance Henriksen (“Aliens”) as Admiral Steven Hackett.