At least three people were killed after tornadoes and powerful storms ripped through hard-hit Oklahoma and continued to churn east  — threatening millions of people from Texas to Wisconsin Thursday. 

Two of the deaths were reported in the small town of Cole and one person died at a hospital in the state’s central Pottawatomie County as entire homes were leveled and thousands were left without power, according to CNN.

The number of casualties following the wild weather Wednesday were expected to rise amid search-and-rescue efforts, Deputy Scott Gibbons with the McClain County Sheriff’s Office told the outlet.

Rescuers on Thursday were responding to reports of “injuries and persons entrapped within their shelters” in areas near Oklahoma City, the McClain County Sheriff’s Office said.

About 20,000 homes and businesses were without power in Oklahoma on Thursday morning, officials said.

The same storm system that wreaked havoc on the state was heading east as of Thursday afternoon — with hail, tornadoes and strong wind potentially striking areas including Dallas, Houston and Chicago, the Storm Prediction Center said.

Cities such as Little Rock, Arkansas, Shreveport, Louisiana and Springfield, Missouri  also face possible severe weather Thursday evening. 

Also impacted by the violent storm system were Kansas and Iowa, where the National Weather Service began issuing tornado warnings late Wednesday.

Four tornado reports were recorded in Iowa and three in Kansas on Wednesday night. Two in Iowa and one in Kansas have been preliminarily confirmed, according to CNN.

People were urged to seek shelter as the twisters bore down on their communities.

Cole resident Barry Harbison said it felt like a roller-coaster when a tornado lifted his trailer home off the ground and tossed it while he was stuck in it.

“I stayed in the bathroom and (the storm) picked up the whole trailer and moved it,” he told KOCO.

Harbison said he found one of his cats but was still searching for two others after the devastation.

Clay Eckeles, a resident of Tuttle, Oklahoma, rushed over to Cole where his nephew lives in a trailer home without a shelter.

“My nephew, stuck in his trailer house, down here down the road. They had to break him out of there. Just waiting for him to walk down the road,” Eckeles told KOCO.

Seth Garret-Bottom, another Cole resident, said he rode out the storm in an above-ground shelter with several other people.

“It sounds cliché, but [it sounded] like a train,” Garret-Bottom told KFOR. “It really did. Just when you start shaking and then the doors move and you can hear just metal clanging around like crazy. It was insane.”

He added: “It’s one of those things, you know, never seen anything like it.”

At least nine tornadoes touched down in Oklahoma on Wednesday, including Shawnee, a city of about 30,000.

More than 30 residents at Brookdale Senior Living, an assisted-living facility in Shawnee were evacuated after the building’s windows were blown out and water swept inside, Executive Director Shelee Stewart told KOCO.

“We’ve been blessed everybody is alive,” Stewart said, adding that there were no major injuries.

Stewart described the staff who helped move residents to the bathrooms during the storm as “heroes,” adding that some suffered minor injuries.

In addition to destroyed homes, power lines also were torn down and trees were toppled over a wide swath.

Oklahoma Baptist University in Shawnee and an airport sustained damage before a tornado moved off.

“We do not have a number of homes or businesses damaged, but we do know that significant damage occurred,” Benny Fulkerson, a spokesperson for the Oklahoma Department of Emergency Management, said in a statement Wednesday night.

The same system that wreaked havoc Wednesday night is heading East Thursday, bringing a severe storm threat for more than 50 million people from Texas to Wisconsin, CNN reported.

With Post Wires