Perspective is everything!

Amanda Knox — whose sensational 2009 murder conviction in Italy was famously overturned — offered some advice to Americans bracing for a loss on Election Night.

“Whatever happens, the next four years can’t be as bad as that four-year study abroad I did in Italy, right?,” Knox quipped on Twitter on Tuesday evening.

Knox aka “Foxy Knoxy,” was studying abroad in Perugia, Italy, in 2007 when she was accused of helping then-beau Raffaele Sollecito kill 21-year-old British roommate Meredith Kercher in a supposed sex game gone awry.

Her conviction was then overturned by an Italian high court in 2011, and she was freed.

The 33-year-old former tabloid sensation recently made headlines again when she joined a bid to help twisted NXIVM sex-cult leader Keith Raniere, who was sentenced to 120 years in prison last week.