At least two people were reported killed — and dozens missing — when a major earthquake struck northern Japan early Thursday.

The magnitude-6.7 earthquake struck the island of Hokkaido at 3:08 a.m., damaging homes, roads and a coal-fired power plant, officials said.

Chief Cabinet Secretary Yoshihide Suga said two were dead, as the quake, the epicenter of which was east of the city of Tomakomai, caused shaking as far away as the area’s capital of Saporro, a city of 1.9 million.

The toll could rise as the Japanese national broadcaster NHK reported that 125 people were injured and nearly 40 are feared missing. Hokkaido’s local disaster agency put the number of injured at 48.

The quake was strong enough to cause landslides on mountains in the area.

Power was knocked out to some 2.9 million households, according to reports — and people were forced to line up outside stores to get food.

“Only a few cartons of instant ramen were left,” said Mika Takeda, who lives in the town of Biei, according to the Associated Press.

Three nuclear reactors were offline for routine safety checks at the time, but are now running on backup generators. After the historic 2011 earthquake and tsunami devastated the country, the Fukushima Dai-ichi nuclear plant melted down.

With Post wires