Customs and Border Protection chief Gregory Bovino is retiring at the end of March after 30 years with the agency in the latest high-profile departure from President Trump’s immigration-enforcement apparatus.

He was forced to leave Minneapolis in January after the Border Patrol shooting of Alex Pretti, an armed anti-ICE protester, who he branded a “domestic terrorist” and claimed he was brandishing a gun at the time he was shot — a contention contradicted by footage of the incident.

Bovino’s departure follows the reassignment of Homeland Security Secretary Kristi Noem, with whom he was closely tied.

President Trump eventually sent border czar Tom Homan to Minnesota to oversee the ICE crackdown, dubbed Operation Metro Surge, after Bovino’s and Noem’s respective exits in an effort to bring down the temperature after protests increased in intensity.

Bovino led Border Patrol’s raids in major US cities including Los Angeles, Chicago, Charlotte, New Orleans and Minneapolis, netting thousands of arrests including convicted gang members, murderers, child sex abusers and more.

“The greatest honor of my entire life was to work alongside Border Patrol agents on the border and in the interior of the United States in some of the most challenging conditions the agency has ever faced,” Bovino, 55, told Breitbart.

Bovino was a highly visible presence in Trump’s nationwide immigration crackdown, and frequently sparred with lefty politicians in sanctuary cities who fought tooth and nail to hamper agents’ enforcement efforts.

“Watching these agents out there giving it their all in some of the most dangerous of environments we have ever faced was humbling,” he told the outlet.

The Department of Homeland Security did not respond to The Post’s request for comment on Bovino’s departure.