The family and friends of a missing South Carolina woman reportedly fear she was last with suspected Long Island serial killer Rex Heuermann — a possibility being investigated by police.

Julia Ann Bean’s daughter immediately recognized Heuermann, 59, when shown a photo of the suspected killer, who owns a home in the Palmetto State, family friend Heidi Kovas told The US Sun.

“I have chills … I’ve seen him,” the daughter replied in text messages viewed by the outlet.

“That was the last man I saw her with personally,” she texted of the night her then-36-year-old mom went missing in June 2017.

“She knew him right away,” Kovas also told PIX 11 of Bean’s daughter, who was not identified and did not speak directly to either outlet.

“She recognized him right away. She said that was the last person she ever saw with her mom.”

Kovas reported what Bean’s daughter told her to officials late Sunday, according to the reports.

“I truly believe Rex Heuermann did something to my friend,” she told The US Sun. “I just want to find my friend.”

Scott Bonner of the Sumter County Sheriff’s Office confirmed that the report was being investigated.

“We’ll be looking into it on our end,” he told PIX 11.

The sheriff’s office did not immediately return The Post’s request for a comment Wednesday, nor did Kovas, Heuermann’s lawyer Michael Brown nor Long Island investigators.

The Suffolk County District Attorney’s Office said it “stands ready to assist outside jurisdictions with any of their ongoing investigations,” while adding it would not comment on any specific inquest.

Heuermann owns property in a wooded area in Chester County, which is about 90 minutes from Sumter, where he reportedly plans to retire.

Although he did not buy that property until 2021, his brother, Craig, has lived in the Chester area since about 2000, records show.

Bean’s daughter last saw her mom at a nail salon in Sumter the night before her high school graduation, Kovas told the US Sun.

Bean arrived in a dark truck driven by a man her daughter now believes to be Heuermann, but who introduced himself with a different name, the family friend said.

Heuermann was first linked to the Gilgo Beach killings by his distinctive dark Chevrolet Avalanche truck, which was hauled away from his South Carolina property soon after his arrest in New York.

Bean’s daughter texted that the mystery man with her mom that night “told me he has lake houses and big boats if I ever wanted to have a boat party.”

He also “offered to take me to a concert and told me he wanted to marry my mom,” the daughter wrote, according to The Sun, which was unable to contact her directly. 

“I never saw her again after that night.”

Despite that being in June, Bean was not reported missing until November 2017.

Bean’s daughter was unaware of Heuermann or the Gilgo Beach case until last week, when Kovas alerted her to how similar the Gilgo Beach victims were to her mom, the family friend said.

“They look like Julia,” Kovas told PIX11 of Maureen Brainard-Barnes, Melissa Barthelemy, Megan Waterman, and Amber Lynn Costello, whose bodies were found wrapped in burlap along Ocean Parkway in Dec. 2010.

“They look just like Julia. The blonde hair, the green eyes, petite.”

Kovas said it was odd that Bean, who struggled with substance abuse, left home without her bag, her phone — and her drugs.

“She always had her drugs. Even her daughter said that she left her dope kit,” the friend said. “She just walked out of her house.”

Kovas also said that her pal “was more than likely escorting.”

“Her daughter mentioned a few different men were giving her money,” she told The US Sun.

“She never told me about doing sex work or anything like that but that’s not something she’d talk with me about anyways,” she said.

“I don’t care what Julie was, I don’t care what Julie did. Julie was still a human being. Julie was still a mother. And now she would be a grandmother,” she said.

“She’s probably dead but there’s still a possibility that she could be out there somewhere,” she said — saying she mostly wants closure for her pal’s kids.

“She has three children that were made to believe their mother had just walked out on them,” she said.

“One of her sons is a Marine and he looks exactly like her. I’ve been in contact with him too and all he kept telling me is how much this means to him, to have someone fighting for their mother.

“She messed up a lot and she was sick. But she did not walk out of their lives without saying goodbye. This wasn’t her choice.”

Kovas did not immediately respond to The Post’s request for an interview.

Shortly after Heuermann was arrested on July 13, investigators began tearing up his South Carolina hideaway, where they also towed away a Chevrolet Avalanche.

Officials are also looking for possible ties between the father of two and cold cases in several states, including Nevada, where Heuermann has long owned timeshares in Las Vegas.

Heuermann has pleaded not guilty to three counts each of first- and second-degree murder.