A wrong-way driver slammed head-on into another car along an Arizona highway Friday, killing five people, including a trio of New Yorkers, authorities said.

A 2010 Nissan zipping against traffic in the westbound lane of Interstate 40 — about 14 miles outside Kingman, in the state’s northwest corner — crunched into a 2015 Honda around 9:10 a.m. local time, officials said.

All five occupants of the two vehicles were killed, according to the Arizona Department of Public Safety.

Harold Wayne Wickham, the 82-year-old driver of the Nissan, and 90-year-old passenger Ella Wickham, both of Laughlin, Nevada, were identified as the occupants of the wrong-way car.

The Honda was driven by Tsun Tong Chan, 57, and had two passengers: Wai Kam Ngai, 54, and Ching Kwong Chan, 21.

All three were from New York, officials said.

The crash, which snarled Interstate 40’s westbound lane for some time, remains under investigation.