At least three people were killed in five separate crashes on a foggy stretch of a Florida highway with zero visibility early Thursday, authorities said.

Multiple wrecks involving at least 17 vehicles, including semi-trucks, shut down the northbound and southbound lanes of I-95 in Volusia County after troopers responded to Edgewater at about 1:30 a.m., WFTV reported.

Three people died in the wrecks and several others, including children, were rushed to hospitals, according to the station, citing Florida Highway Patrol officials.

A Jeep Wrangler and a semi-truck were involved in one of the southbound collisions and both drivers died from their injuries, WFTV reported.

Another person was killed in a crash on the northbound side of I-95 and a child was airlifted to a nearby hospital in stable condition, authorities told the station.

One of the crashes involved a semi-truck that caught fire and exploded, sending a huge plume of smoke into the air, video shows.

Traffic will be closed on I-95 in both directions in southern Volusia County for the next several hours, the Volusia County Sheriff’s Office said early Thursday.

“Please avoid these areas and use extra caution,” department officials said in a statement. “More info will be released when it becomes available.”

A message seeking additional details from the Florida Highway Patrol was not immediately returned.

Foggy conditions and smoke from a recent controlled burn in the area drastically reduced visibility in both directions on the highway, WKMG reported.

Another video posted by WFTV showed one semi-truck involved in one of the fatal crashes with significant damage to its cab. Florida Highway Patrol officials blame “thick fog” overnight for the series of wrecks, WFTV reported.