Johnson pledged "to find common ground" with his Democratic colleagues in his opening speech as House speaker.
He also thanked his predecessor, Kevin McCarthy, for his service, as well as his Republican colleagues and members of his family.
"I want to thank my wife," Johnson also said. "She's not here, couldn't get a flight in time, this happened kind of suddenly."
"I will not let you down," he affirmed to everyone listening.
Johnson went on to share poignant memories of his father, who died of cancer three days before he was first elected to Congress and being overwhelmed with the "weight of history" while serving in the lower chamber.
"At one time, [Americans] had great pride in this institution, but that now is in jeopardy," he said, noting conflicts abroad, a "broken" southern border and out-of-control federal spending.
"The country demands strong leadership of this body — and we must not waver," Johnson added, before saying that his first move as speaker would be to pass a resolution affirming Israel's right to self-defense.
"My office is going to be known for trust, transparency and accountability, for good stewardship," he concluded.
"Let the enemies of freedom around the world hear us loud and clear: The People's House is back in business."