One person was killed and seven others were wounded in several shootings throughout the Big Apple on a violent Friday night.

Four men were shot — one fatally in a shooting in Queens on Friday afternoon that police say may be gang-related.

The four victims — aged 29, 33, 33 and 39 — were standing around a vehicle outside of 117-29 143rd St. in South Jamaica when a gunman approached them and opened fire around 3:15 p.m., NYPD Assistant Chief Kevin Williams told reporters at a brief press conference.

They were rushed to Jamaica Hospital, where one of the 33-year-old men died.

The second 33-year-old is in critical condition and the other two victims are in stable condition, according to police.

The shooter fled the scene on foot and no arrests have been made, Williams said.

Williams said the shooting may have a “gang nexus” and that “several of the individuals who were shot are known to police,” based on the department’s preliminary investigation.

A gun and several shell casings were recovered at the scene.

A few hours later, another three males were shot in upper Manhattan, according to police.

Police responded to a report of multiple people shot 120 Sherman Ave. in Inwood around 6 p.m., cops said.

At the scene, police found two males with graze wounds to the head and another male with a gunshot wound to the arm.

The trio were taken to Harlem Hospital in stable condition. No arrests have been made.

In Brooklyn, a man was shot in the chest near Flatbush Ave, and Farragut Road just before 7 p.m., according to police.

The victim was taken to Kings County Hospital in stable condition. No arrests were made.