The serial burglar charged with breaking into Robert De Niro’s Manhattan townhouse was ordered held on $40,000 bail — after prosecutors warned she’ll just commit another crime if she’s allowed to go free.

Shanice Aviles, 30, who has at least 26 busts on her rap sheet, was given many opportunities to take part in programs that would keep her out of jail before she was charged with second-degree burglary in the brazen Monday morning heist, Manhattan prosecutors said at her arraignment.

“She has repeatedly failed to take advantage of the rehabilitative services that enable her to detox and stay out of trouble and appear [for] court dates,” Manhattan Assistant District Attorney Dylan Los Huertos told the judge.

“The defendant demonstrated that she will not engage with services,” Los Huertos said. “She will not return to court and she will re-offend if she is released.”

The prosecutor asked Manhattan Criminal Court Judge Melissa Lewis to hold Aviles on $40,000 cash bail or bonds of $80,000 or $120,000, with Lewis signing off on the recommendation.

“There is no least restrictive means other than monetary bail,” Los Huertos said. “We have tried everything else, therefore significant cash bail is appropriate here.”

Aviles was last released on Dec. 13 after a judge waived her $5,000 bail for her to check into a Manhattan drug treatment program — which she blew off, officials said.

In court late Monday on the new charge, Lewis told Aviles’ Legal Aid lawyer that his client “has been given numerous opportunities” in the past.

“They gave the defendant an opportunity to attend an in-patient program,” Lewis told Aviles’ lawyer. “Unfortunately, [she] warranted and we have a new matter in front of us.”

Aviles was nabbed by cops after eagle-eyed officers saw her break into the $69,000-a-month East 65th Street townhouse and caught her sporting a pair of stolen headphones, according to a criminal complaint in the case.

The “Goodfellas” actor was upstairs sleeping when he heard the commotion and came downstairs — just in time to see cops take Aviles into custody, sources said.

Aviles faces up to 15 years in prison if convicted of the top charge.

The career felon, who has 16 busts this year alone, shrugged off the new case when she was led out of the NYPD’s 19th Precinct stationhouse in handcuffs on Monday.

“I didn’t murder anybody!” she yelled at reporters. “I didn’t go to Robert De Niro’s house!” 

The 79-year-old Oscar-winning actor remained inside the home most of the day Monday, at one point stepping out and telling reporters he was “OK” following the incident.

On Tuesday, workers came to the house at 8:15 a.m. but someone else answered the door.

About an hour later, a dog walker stopped by to walk the actor’s pups.

De Niro left the house and ducked into a black SUV around 11:45 a.m. without saying a word.

Additional reporting by Desheania Andrews and Elizabeth Rosner