Manhattan federal prosecutors have supercharged their efforts to ​ultimately ​put alleged West Side terrorist Sayfullo Saipov to death with an indictment handed up Tuesday that charges him with an additional 20 counts, including murder and attempted murder.

Under the grand jury indictment, Saipov, 29, now faces ​eight counts of murder in aid of racketeering — all of which carry the potential for life in prison or death — as well as one count of violence and destruction of motor vehicle, which also comes with a potential death sentence.

In total, he faces 22 counts — up from the two counts he was charged with initially.

Previously, only one of the two counts he faced — for violence and destruction of motor vehicle — carried the potential for death or life in prison.

The Patterson, NJ, resident was arrested on Halloween after he allegedly killed eight people and inured a dozen by speeding over a popular bike-only path in lower Manhattan in a rental truck.

The Uzbeki national, who was taken into custody after he was shot by NYPD, was so shameless about his loyalty to ISIS in the aftermath of the attack that he asked if he could fly the terror group’s flag inside his Bellevue Hospital room, the feds have said.

“As alleged in this indictment, Sayfullo Saipov murdered eight innocent people and injured many more in a calculated act of terrorism in the heart of one of our great cities,” US Attorney General Jeff Sessions said of Tuesday’s indictment.

“Like New York City’s response to his alleged attack, we expect that justice in this case will be swift, firm, and resolute,” Acting Manhattan US Attorney Joon Kim vowed.