A 70-year-old minivan driver and his wife were killed in a horrific car accident early this morning in the Bronx, police said.

The driver, Sixto De La Cruz, lost control of his vehicle and smashed into a concrete median on the Grand Concourse near 165th Street at 5:48 a.m., cops said.

De La Cruz was taken to Lincoln Hospital. His wife Brigida was rushed to Bronx Lebanon Hospital.

Cops said no criminality is suspected.