Three people were hurt — two seriously — in a horrific car crash on the Manhattan side of the George Washington Bridge, officials said.

The accident happened around 2:20 a.m. Monday on an approach to the bridge near West 180th Street and Amsterdam Avenue, the FDNY said.

The car apparently struck a divider, shredding the vehicle to bits.

Three people had to be pulled from the mangled wreckage and were rushed to Harlem Hospital. Two of the victims were listed in serious condition, officials said.

A pink backpack — apparently belonging to a child — was found at the accident scene. The ages and genders of the injured were not immediately available, police said.

The crash is still under investigation.