On Friday, Gov. Andrew Cuomo nominated his longtime aide and chief of staff to head the state’s top Wall Street regulator starting next month — a personnel change that signals an aggressive stance toward the financial sector.

Linda Lacewell, a former Justice Department prosecutor who once led the case against Enron, is slated to take over the Department of Financial Services starting Feb. 1, when the current superintendent, Maria Vullo, steps down.

The Hell’s Kitchen resident would likely start in an acting capacity until her nomination is approved by the state Senate, though it’s unclear when that vote would happen.

Lacewell, 55, has been prosecuting some of New York’s most high-profile corruption cases since 2007, when she first started working for then-Attorney General Cuomo.

The nomination was announced quietly Friday on a list that included 15 other personnel changes for Cuomo’s third term — a distinct change from the introduction of Lacewell’s predecessors, Vullo and Ben Lawsky.

“Linda is a brilliant and dedicated public servant who’s been an integral member of the Governor’s senior leadership team for nearly a decade,” said Melissa DeRosa, secretary to Cuomo.