Mayor de Blasio cleaned house at the city’s Human Rights Commission Friday.

The mayor appointed workplace-discrimination attorney Carmelyn Malalis as chair of the agency, which enforces local civil-rights laws.

She replaces Patricia Gatling, a holdover from the Bloomberg administration, who was hailed for tackling a backlog of 5,000 cases when she began her tenure in 2002, but whose leadership has been questioned of late.

Earlier this month, Public Advocate Letitia James and other critics denounced the agency as languishing and ineffective, based in part on its low rate of substantiating discrimination.