An unhinged woman was booted from Sean “Diddy” Combs’ bombshell Manhattan trial Tuesday after she started hurling expletives – warning the disgraced music mogul that “these motherf–kers are laughing at you.”

The unidentified woman was thrown out of the Manhattan federal courtroom just as testimony was set to kick off for day 15 of testimony in Combs’ high-profile federal sex-trafficking and racketeering conspiracy trial.

“Diddy, these motherf–kers are laughing at you!” she screamed.

She also railed against the “system” just moments before the judge ordered her to be removed.

The Bad Boy Records founder, who was wearing a brown sweater over a white button-down shirt, turned around and stared at the woman as she ranted.

In the moments before the wild outburst, court marshals could be heard warning her, “Don’t do it.”

The jury wasn’t in the courtroom at the time.

The disruption unfolded right before a security guard working at the ritzy Los Angeles hotel where Combs was infamously caught on video brutally beating and kicking then-girlfriend Cassie Ventura took the stand.

Eddy Garcia, who worked in private security at the InterContinental Hotel, testified that Combs and his chief of staff, Kristina Khorram, hounded him to get ahold of the now-infamous surveillance video after the March 5, 2016 beating.

Garcia told jurors that Combs had called him once promising that “he would take care of me” if he helped get rid of the video.

“He said something like this could ruin him. He was concerned that this video could get out and that it could ruin his career,” the guard told the court.

Combs, 55, is accused of using his fame, fortune and many businesses to run a decade-long scheme in which he controlled and manipulated Ventura into drug-fueled “freak-off” sex marathons that went on for days.

The disgraced rapper, who has pleaded not guilty, faces life in prison if convicted.