A 3-year-old boy was killed in his stroller and his mother was injured Monday when a pickup truck plowed into them in an East Harlem crosswalk, cops said.

A Ford F-250 driven by Jaime Sabogal, 59, of Yonkers, struck Bertin DeJesus near First Avenue and 116th Street at about 9:35 a.m., according to police.

The child was pronounced dead at Metropolitan Hospital, where his 25-year-old mother was treated for minor injuries.

“She’s in stable condition,” said hospital spokesman Noah Alicea, who declined to describe the mom’s specific condition. “[Bertin] took the brunt of the injuries.”

A worker at a neighborhood Dunkin’ Donuts said the woman is a regular customer who stopped by moments before the accident.

“She’s here every day. She ordered two bagels with cream cheese with her friend and hash browns for the baby this morning,” Marisol Medina, 51, told The Post. “They said goodbye to me. I said ‘Be careful,’ in Spanish.”

A short time later, “everyone was screaming,” Medina said.

“When I came over to see, I saw her, she was on the floor holding the baby and screaming,” she said about the distraught mother, who was covered in blood and screaming, “Save my baby! Save my baby!”

“I was destroyed. Not only do I see her all the time, she is one of my closest customers,” Medina said, adding that the woman’s leg was injured. “She always ordered medium coffee with sugar.”

A neighbor at the family’s East Harlem apartment building recalled how Bertin was “always very happy.”

“He waves to neighbors and can be shy sometimes, but a happy boy,” said the neighbor, who declined to give her name.

A stroller with a rain shield remained in the middle of the intersection as police investigated the crash.

Medina said she doubts Sabogal saw the woman crossing the street with her son.

Sabogal, who remained at the scene, was taken into custody following the collision. He was charged with aggravated unlicensed operation of a motor vehicle, failure to yield to a pedestrian and failure to exercise due caution.

He was given a desk appearance and released.