The “Fame” high school has a new principal, one who promises to sing a new tune after her embattled predecessor got the boot, The Post has learned.

Yeou-Jey Vasconcelos, 38, was appointed Thursday to lead Fiorello H. Laguardia High School Of Music & Art and Performing Arts, the NYC institution that inspired the 1980 movie “Fame” and a TV series that ran for six seasons on NBC.

A galaxy of stars have graduated from the elite school — Al Pacino, Liza Minelli, Jennifer Aniston, Nicki Minaj, and Adrien Brody, to name a few.

Vasconcelos, a pianist, previously served as principal of Talented Unlimited HS, another top-performing arts public school in Manhattan, for four years. Before that, she worked at high-performing Eleanor Roosevelt High School for 10 years, including as music director.

She was named acting principal of LaGuardia in July, two weeks after the Department of Education ousted the controversial Lisa Mars, pending a search for a permanent replacement.

Vasoncelos has since endeared herself to the faculty.

“She’s 180 degrees from her predecessor,” said music teacher Paula Washington, a faculty leader.

“She’s honest. She listens. She is collaborative  She has humility. She has compassion. She’s a team player.”

On a recent Friday, when live music is performed in the school lobby, Vasconcelos played the piano to accompany student cellist Giorgio Poma.

“She showed us that she had chops, but she didn’t have to be the main event. That spoke volumes,” Washington said.

Vasconcelos, who is pregnant and due in December, worked over the summer to interview replacements for 45 faculty members who had left under Mars.

In a letter to parents, students and staff on Friday, Manhattan high schools superintendent Vivian Orlen heaped praise on Vasconcelos, saying she is an “open, strong communicator, great listener, responsive, inclusive, understands the mission and vision of our school and ‘actually likes teenagers.'”

Mars had generated complaints for years that she was diminishing LaGuardia’s emphasis on the arts — and student talent — while stressing academic achievement instead.

The controversy boiled over last May when hundreds of students walked out of classes and held a hallway sit-in. In June, Mars did not attend the school’s graduation ceremony.

But Mars did have support from some parent leaders, who argued the arts were not being “sacrificed for academics.”

“We put on the best shows in town. Our students get into the nation’s top conservatories” former Parent Association president Linda Hahn once told The Post.

LaGuardia is one of New York City’s nine specialized high schools, but the only one that doesn’t use the SHSAT, the entrance exam used solely to determine admission. Under state law, candidates must show satisfactory grades and state test scores as well as audition or submit an arts portfolio.

Vasconcelos could not be reached immediately for comment.